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Author: Claude (AI), from PubMed abstracts · Reviewed by: Dr Mina Abdelmseih · Reviewed: 2026-11-15 · Review due: 2027-11-15

Educational content only. Not personalised medical advice. Clinical decisions remain the responsibility of the treating clinician.

Entropion and Ectropion

Entropion is inward turning of the eyelid margin against the globe; ectropion is outward turning, usually of the lower lid [S10] [S9]. Both are common in older people and becoming more common with population ageing [S10] [S9]. Malpositions such as cicatricial entropion and paralytic lid deformity can cause exposure, inflammation and significant visual impairment [S12].

Key points - Entropion is involutional, cicatricial, spastic or congenital; involutional is the most common [S10]. - Acquired ectropion is involutional, paralytic, mechanical or cicatricial; involutional is the most common [S9]. - Lid instability usually comes from horizontal laxity or from disinsertion or attenuation of the lower lid retractors, so surgery should correct horizontal and vertical instability [S1]. - In the only RCT, everting sutures plus lateral tarsal strip was more effective for involutional entropion than everting sutures alone [S2].

Evidence last checked: 2026-10-17 (PubMed abstracts).

Red flags

Recognise it

Three side views of the front of the eye and lower lid: normal, with lashes pointing forward; entropion, with the lid rolled in and lashes against the cornea; and ectropion, with the lid tilted away from the eye and its inner surface exposed.
Side views of the lower lid. In entropion the lid margin turns inward so the lashes rub the cornea; in ectropion the lid turns outward, away from the globe. Original illustration (schematic), not a photograph or scan of a real patient. Easy Ophthalmology; drawn by Claude (AI), 2026-10-18; awaiting the Editor-in-Chief's review.

Entropion - Involutional entropion is one of the commonest lower lid malpositions in the elderly [S2]. Asian eyelids develop it more often [S3]. - Proposed causes: vertical and horizontal lid laxity and preseptal orbicularis overriding the pretarsal orbicularis [S5]. Retractor attenuation appears to be the predominant factor in most patients; tarsal atrophy, enophthalmos and fat prolapse may contribute in some [S11]. - Cicatricial entropion arises from posterior lamellar contraction after inflammatory or iatrogenic injury [S12].

Ectropion - Involutional ectropion is caused by age-related degeneration of periocular tissues, with horizontal and vertical factors [S7]. - Cicatricial ectropion occurs when a scar below the eye pulls the lid down enough to evert it [S6]. - Paralytic: facial nerve palsy causes incomplete blinking, punctal malposition and lacrimal pump dysfunction, with tearing and ocular surface instability [S12].

Confirm it

Manage it

Before acting on this section, check the national and local guidelines, product information and regulatory approvals that apply where you practise. See the medical disclaimer.

Tier A (primary care / no specialist)

Tier B (general eye clinic)

Tier C (specialist centre)

Refer when

Situation Urgency
Entropion or exposure with corneal ulcer or reduced vision Same-day
New facial palsy with incomplete lid closure Within days, to an ophthalmologist, shortly after diagnosis [S8]
Symptomatic involutional entropion without corneal damage Routine; timing per your local service or specialist advice
Ectropion with tearing or irritation, cornea healthy Routine; timing per your local service or specialist advice

Pitfalls

Evidence notes

Source Date Design
[S1] 2006 Narrative review
[S2] 2011 Cochrane systematic review, one RCT
[S3] 2015 Narrative review
[S4] 2016 Case series, 11 patients
[S5] 2019 Literature review
[S6] 2020 Literature review (41 articles)
[S7] 2023 Literature review
[S8] 2023 Narrative review, facial palsy
[S9] 2024 Clinical review
[S10] 2024 Clinical review
[S11] 2025 Literature review with author observations
[S12] 2025 Narrative review (115 publications)

Related articles

References

See the numbered source list below. Each marker [S#] links to its PubMed and DOI record.

Sources

  1. [S1] Piskiniene R Eyelid malposition: lower lid entropion and ectropion. Medicina (Kaunas, Lithuania). (2006). PubMed 17172788
  2. [S2] Boboridis KG, Bunce C Interventions for involutional lower lid entropion. The Cochrane database of systematic reviews. (2011). PubMed 22161369 · doi:10.1002/14651858.cd002221.pub2
  3. [S3] Marcet MM, Phelps PO, Lai JS Involutional entropion: risk factors and surgical remedies. Current opinion in ophthalmology. (2015). PubMed 26154839 · doi:10.1097/icu.0000000000000186
  4. [S4] Iozzo I, Tengattini V, Antonucci VA Senile lower lid entropion successfully treated with botulinum toxin A. Journal of cosmetic dermatology. (2016). PubMed 26777720 · doi:10.1111/jocd.12210
  5. [S5] Lin P, Kitaguchi Y, Mupas-Uy J, Sabundayo MS, Takahashi Y, Kakizaki H Involutional lower eyelid entropion: causative factors and therapeutic management. International ophthalmology. (2019). PubMed 30315389 · doi:10.1007/s10792-018-1004-1
  6. [S6] Kooistra LJ, Scott JF, Bordeaux JS Cicatricial Ectropion Repair for Dermatologic Surgeons. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. (2020). PubMed 31517657 · doi:10.1097/dss.0000000000002150
  7. [S7] AlHarthi AS Involutional ectropion: etiological factors and therapeutic management. International ophthalmology. (2023). PubMed 36053479 · doi:10.1007/s10792-022-02475-3
  8. [S8] Moncaliano MC, Ding P, Goshe JM, Genther DJ, Ciolek PJ, Byrne PJ Clinical features, evaluation, and management of ophthalmic complications of facial paralysis: A review. Journal of plastic, reconstructive & aesthetic surgery : JPRAS. (2023). PubMed 37931512 · doi:10.1016/j.bjps.2023.10.102
  9. [S9] Khan AZ, Ueland HO, Bohman E, Tønseth KA, Utheim TP Ectropion. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke. (2024). PubMed 38258716 · doi:10.4045/tidsskr.23.0309
  10. [S10] Khan AZ, Ueland HO, Bohman E, Tønseth KA, Utheim TP Entropion. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke. (2024). PubMed 39692657 · doi:10.4045/tidsskr.24.0191
  11. [S11] Custer PL Observations on the Etiology of Involutional Entropion. Ophthalmic plastic and reconstructive surgery. (2025). PubMed 39700401 · doi:10.1097/iop.0000000000002859
  12. [S12] Quaranta Leoni FM, Marabottini N, Iuliano A, Strianese D, Savino G Eyelid Malpositions and Ocular Surface Disease: Clinical Correlations and Management Strategies. Journal of clinical medicine. (2025). PubMed 41375826 · doi:10.3390/jcm14238523

Guidelines

  1. [G1] NHS Scotland (Community Eyecare Guidelines, eyes.nhs.scot). 1.6 Entropion (2026). https://www.eyes.nhs.scot/eyecare-guidelines/section-1-eyelids/16-entropion/